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How Raising One Biomarker (what could it be?) Helps Fight Cancer. The Molecular and Physiological Truth Behind Oxygen Efficiency and Cancer Risk.
April 25, 2025 · 24 min

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Episode description

How Raising Your VO₂ Max Helps Fight CancerThe Molecular and Physiological Truth Behind Oxygen Efficiency and Cancer Risk

In this breakthrough episode of The New Science of Physical Health, host Shane Stubbs reveals how oxygen efficiency—measured by your VO₂ Max—can be one of the most powerful tools in the fight against cancer.

Forget the idea that VO₂ Max is just for athletes. Shane breaks down the molecular, hormonal, and immune system upgrades that occur when you increase your cardiorespiratory fitness—and how these changes can reduce your cancer risk by up to 70%.

This episode will completely reframe how you think about exercise, fitness, and long-term disease protection.

The Oxygen Efficiency Score that predicts disease risk

How low VO₂ Max signals inflammation, poor immunity, and metabolic dysfunction

Why improving VO₂ Max triggers systemic resilience

How myokines fight chronic inflammation

Reprogramming insulin and IGF-1 to reduce cancer fuel

Antioxidant enzymes and DNA repair via improved oxygen efficiency

Activation of p53: your body’s anti-cancer gene

Enhanced immune surveillance: NK cells, T-cells, and macrophages

Oxygen-rich internal environment = less cancer growth

Fat loss and hormone balance that detoxifies your biology

45% lower cancer risk with high VO₂ Max

55% lower cancer mortality in fit individuals

Up to 70% reduction in recurrence risk after treatment

From a VO₂ Max of 33 to 50—and aiming for 60 by age 60

How targeted high-intensity training reshaped his internal biology

Why VO₂ Max training is his personal cancer prevention plan

How to track VO₂ Max and earn AQ Points

Ideal training zones (Zone 3–5)

Weekly targets for adaptation

Why consistency beats intensity

VO₂ Max isn’t just a fitness number—it’s a biological shield against cancer.Every point you increase makes your internal environment less friendly to disease—and more resilient to illness, aging, and cellular damage.

Estimate or track your VO₂ Max (smartwatch, software, or test)

Earn 100–150 AQ Points weekly

Train 2–3x per week in Zones 3–5

Focus on oxygen delivery, not calorie burn

Stay consistent—adaptation builds over time

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Free VO₂ Max lesson & AQ Tracker

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If this sparked something in you, share it with someone you love.You might help them take the first step toward a body that’s biologically hostile to cancer.

🎧 Subscribe on Apple, Spotify, or YouTube📩 Get exclusive access and weekly VO₂ Max strategies at PerfectHealthLesson.com